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  • Title: The choice of therapy in medically intractable trigeminal neuralgia.
    Author: Rappaport ZH.
    Journal: Isr J Med Sci; 1996 Dec; 32(12):1232-4. PubMed ID: 9007161.
    Abstract:
    Trigeminal neuralgia stands out as one of the few severe neuropathic pain states for which successful treatment options are available. Up to one-half of patients become refractory to medical therapy over time. At this point, the question of which intervention is appropriate becomes an important issue. A personal series of 150 patients treated between 1988 and 1995 is reviewed. Patients under 65 years and in good general health underwent surgery for microvascular decompression of the trigeminal root; in the remaining 120 patients glycerol was injected percutaneously into the trigeminal cistern. The results in these two patient groups is presented and the rationale of choosing an operative versus a percutaneous procedure is discussed in light of the outcome in this series and in the literature.
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