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  • Title: Borna disease virus RNA in peripheral blood mononuclear cells obtained from healthy dairy cattle.
    Author: Hagiwara K, Nakaya T, Nakamura Y, Asahi S, Takahashi H, Ishihara C, Ikuta K.
    Journal: Med Microbiol Immunol; 1996 Nov; 185(3):145-51. PubMed ID: 9007819.
    Abstract:
    We examined natural infection of Borna disease virus (BDV) in 74 healthy dairy cattle in Japan. The seroprevalence determined using recombinant BDV p24 protein was 20.3%. The prevalence of BDV RNA in peripheral blood mononuclear cells (PBMCs) determined by polymerase chain reaction for p24 was 10.8%. Cell fraction of the PBMCs revealed the presence of BDV RNA in the T cell-enriched fraction. Thus, BDV infection is widespread even among healthy cattle.
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