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  • Title: The surgical resectability of meningiomas of the cavernous sinus.
    Author: O'Sullivan MG, van Loveren HR, Tew JM.
    Journal: Neurosurgery; 1997 Feb; 40(2):238-44; discussion 245-7. PubMed ID: 9007855.
    Abstract:
    OBJECTIVE: The optimal management for patients with cavernous sinus meningiomas remains controversial. We attempt to contribute to the ongoing debate of appropriate surgical indications. METHODS: In this retrospective review, 39 patients, including 27 women and 12 men ranging in age from 24 to 73 years (median, 48 yr), underwent surgical treatment for this condition. Completeness of tumor resection, cranial nerve morbidity, general morbidity, and long-term outcome were studied. The cavernous internal carotid artery was partially encased in 15 patients, totally encased in 11 patients, and narrowed by tumor in 13 patients. RESULTS: Of eight patients who underwent complete tumor resection, seven had partial encasement of the internal carotid artery. Of 31 patients who underwent subtotal resection, 11 underwent postoperative radiotherapy. There were no deaths in the series. Morbidity was 17.9% for cranial nerves controlling extraocular motor function. Trigeminal nerve function did not improve after surgical treatment. The median follow-up period was 2 years (range, 6 mo-5.3 yr). Symptomatic and radiographic recurrence occurred in two patients who underwent complete tumor resection and in two patients who underwent subtotal resection. CONCLUSION: Based on our findings and a review of the literature, we conclude the following: 1) the resectability of meningiomas of the cavernous sinus depends on the degree of internal carotid artery involvement; 2) total excision of cavernous sinus meningiomas is possible but rarely achieved in holocavernous meningiomas; 3) cranial nerve morbidity is significant; and 4) subtotal excision with or without postoperative radiotherapy is an effective short-term oncological strategy.
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