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  • Title: Duration of immunity in foxes vaccinated orally with ERA vaccine in a bait.
    Author: Lawson KF, Chiu H, Crosgrey SJ, Matson M, Casey GA, Campbell JB.
    Journal: Can J Vet Res; 1997 Jan; 61(1):39-42. PubMed ID: 9008799.
    Abstract:
    Red foxes (Vulpes vulpes) vaccinated orally with the ERA strain of rabies vaccine in a bait were challenged after 83 mo. Ten of 11 foxes that had seroconverted following vaccination resisted challenge with a virulent rabies virus which produced clinical signs of rabies in 6 of 6 unvaccinated foxes. Five of 11 vaccinated animals retained titers of rabies virus neutralizing antibody throughout the period. Although 6 of 11 had no detectable antibody at the time of challenge, 5 of these 6 resisted challenge and had an anamnestic response, as indicated by elevated titers of antibody when measured at day 77 postchallenge. These results show that foxes can be immunized successfully with a single oral dose of ERA vaccine, probably with protection against a lethal rabies challenge, for at least 7 y.
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