These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Urokinase thrombolysis as initial therapy for acute and non-acute ischemic extremities.
    Author: Byrne D, Byrne WD, Kiernan PD, Harshaw W, Bryne J, Fulcher T, Stanton L, Goodman S, Karnaze M.
    Journal: Va Med Q; 1997; 124(1):41-4. PubMed ID: 9009854.
    Abstract:
    Limb ischemia, both acute and chronic, presents a risk to life and limb with mortality rates from 3% to 37% and amputation rates of the same range. Our experience with urokinase thrombolysis as the initial therapy for acute and non-acute ischemic extremities over 57 consecutive cases of native arterial occlusion by either thrombus or embolus has resulted in no mortality and only 3.5% requiring amputation (2 of 57). In 74% of cases initial thrombolytic therapy was followed by either balloon angioplasty (35 patients) or surgery (7 patients) to relieve the underlying cause of obstruction (i.e., stenosis, occlusion or aneurysm). Thrombolysis alone was sufficient and effective treatment in the remaining 26% (15 patients).
    [Abstract] [Full Text] [Related] [New Search]