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  • Title: Treatment of respiratory failure due to respiratory syncytial virus pneumonia with natural surfactant.
    Author: Vos GD, Rijtema MN, Blanco CE.
    Journal: Pediatr Pulmonol; 1996 Dec; 22(6):412-5. PubMed ID: 9016476.
    Abstract:
    We describe two infants suffering from severe pneumonia caused by respiratory syncytial virus (RSV) infection and needing mechanical ventilation with both high ventilator settings and a high fraction of inspired oxygen. The severity of the respiratory failure and the possibility of decreased and/or altered surfactant production led us to treat these infants with intratracheal instillation of natural surfactant. This resulted in an improvement of lung compliance and a decrease in the amount of oxygen required to maintain acceptable oxygen saturations. Intratracheal surfactant instillation might, therefore, be useful in the treatment of severe RSV pneumonia.
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