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  • Title: Chromogenic lactate-leukocyte esterase substrates.
    Author: Johnson GM, Schaeper R.
    Journal: Bioconjug Chem; 1997; 8(1):76-80. PubMed ID: 9026039.
    Abstract:
    The first successful reported use of lactate-based chromogenic, colorimetric substrates for a serine protease-based enzyme is described. A series of hydroxy-protected 5-phenyl-3-hydroxypyrrolyl L-lactate substrates of the general formula RO-Lac-OPP were prepared and formulated into reagents for the determination of leukocytes in dry phase formats.
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