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  • Title: [The significance of exacerbations of lung diseases in the development of chronic cor pulmonale and their treatment].
    Author: Ershov AI, Evstaf'ev IuA, Sobkin AL, Grigor'ev IuG.
    Journal: Probl Tuberk; 1996; (4):14-6. PubMed ID: 9026794.
    Abstract:
    In 61 patients, pulmonary tuberculosis was complicated by thrombosis of the pulmonary artery or its embolism and by bronchial asthma. In various lung diseases, there was a combination of some factors predisposing to chronic cor pulmonale. These included specific infection, sympathoadrenal activation, reduced capillaries, and hypoxia in pulmonary tuberculosis, alveolar hypoventilation with arteriolar spasms, and elevated intrathoracic pressure in bronchial asthma; higher pulmonary arterial systolic pressure due to spasms of the pulmonary branches and drastically reduced arterial bed in pulmonary thromboembolism.
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