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  • Title: Increased anion gap after liver transplantation.
    Author: Kirschbaum B.
    Journal: Am J Med Sci; 1997 Feb; 313(2):107-10. PubMed ID: 9030677.
    Abstract:
    Massive fibrinolysis after a liver transplant resulted in oliguric renal failure and necessitated the continuous infusion of large quantities of fresh frozen plasma. With the increase in plasma protein concentration, there was a simultaneous increase in the anion gap. These two parameters, the anion gap and total protein or albumin level in the blood, demonstrated a high degree of correlation. Weaker but significant correlations were found in a retrospective analysis of patients with a variety of renal diseases and a population of long-term peritoneal but not hemodialysis patients. This entity of hyperproteinemic acidosis should be added to the list of high anion gap acidoses.
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