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  • Title: Syringomyelia developing as an acute complication of tuberculous meningitis.
    Author: Daif AK, al Rajeh S, Ogunniyi A, al Boukai A, al Tahan A.
    Journal: Can J Neurol Sci; 1997 Feb; 24(1):73-6. PubMed ID: 9043754.
    Abstract:
    BACKGROUND: Tuberculosis of the nervous system has protean manifestations. Syringomyelia, though an uncommon complication of it, is usually of late onset. METHODS: We report two patients with tuberculosis meningitis who developed syringomyelia acutely. The diagnosis was supported by neuroimaging and findings at laminectomy. RESULTS: The two patients developed syringomyelia between 11 days and 6 weeks of the onset of tuberculous meningitis. They both had cord swelling and softening. CONCLUSIONS: Acute-onset syringomyelia should be suspected in any patient being treated for tuberculosis meningitis who subsequently develops limb weakness and/or sphincteric dysfunction. Inflammatory edema and cord ischemia appeared to be the underlying mechanisms in these early onset cases rather than arachnoiditis which is important in late-onset cases.
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