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  • Title: Life-threatening anaemia caused by B19 parvovirus infection in a non-immunocompromised patient.
    Author: Biesma DH, Nieuwenhuis HK.
    Journal: Neth J Med; 1997 Feb; 50(2):81-4. PubMed ID: 9050335.
    Abstract:
    A 21-year-old Surinam boy suffering from a combined heterozygous sickle-cell beta-thalassaemia presented with an extreme anaemia (haemoglobin concentration 0.7 mmol/l) and severe haemolysis without signs of increased erythropoiesis. An acute B19 parvovirus infection was diagnosed by a transient increase of IgM anti-B19 parvovirus titres and a positive polymerase chain reaction for B19 parvovirus. The patient recovered spontaneously after a short period of supportive care with red cell transfusions and mechanical ventilation.
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