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  • Title: 4-(p-Chlorophenylthio)butanol (W-2719), a new non-antihistaminic drug for immediate hypersensitivity allergies.
    Author: Fukui GM, Ludwig BJ, Sofia RD, Reisner DB, Berger FM.
    Journal: Arzneimittelforschung; 1979; 29(6):912-7. PubMed ID: 90512.
    Abstract:
    p-Chlorophenylthiobutanol (W-2719) has been found to effectively inhibit immunologic and non-immunologic histamine release and mast cell degranulation. It has been found to effectively suppress passive cutaneous anaphylaxis (PCA) reaction not be antihistaminic action, but by inhibiting the release of allergic mediators.
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