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  • Title: Sesquiterpene lactones. Part XV. New cytostatic active sesquiterpene lactone from herb of Anthemis nobilis L.
    Author: Grabarczyk H, Drozdz B, Hladoń B, Wojciechowska J.
    Journal: Pol J Pharmacol Pharm; 1977; 29(4):419-23. PubMed ID: 905207.
    Abstract:
    From fresh and dried herb (without inflorescences) of Anthemis nobilis L. a new sesquiterpene lactone C20H26O6 was isolated. This compound showed a cytotoxic activity at a level of ED50 HeLa -- 0-56 microgram/ml (1-5 x 10(-6) M), and ED50 KB -- 1.23 microgram/ml (3-5 x 10(-6) M), what qualifies it for further in vivo studies.
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