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  • Title: [Dynamics of EKG changes in patients with Itsenko-Cushing disease before surgery, and following the 1st and 2d stages of adrenalectomy].
    Author: Slavina ES, Kuratev LV, Kazeev KN, Kertsman VI, Iundunov VM.
    Journal: Probl Endokrinol (Mosk); 1977; 23(4):35-9. PubMed ID: 905258.
    Abstract:
    The results of examination of ECG in 44 patients suffering from Itsenko-Cushing's disease at different stages of surgical treatment are presented. The data obtained were compared with the blood potassium and sodium levels, 17-KS, and 17-OCS levels in the urine, arterial pressure and cholesterol content. Various ECG changes before the operation were revealed in 39 patients. Signs of enlargement of the left ventricle and deformity of the end part of the ventricular complex (negative T wave and or reduction of S-T segment in I, II, avL V5-6 leads) were found in 8 patients, and deformity of the end part of the ventricular complex without any signs of enlargement of the left ventricle--in 18 patients. There proved to be a significant dependence of the changes in the end port of the ventricular complex on increased urinary excretion of 17-OCS, hypokaliemia and hypernatriemia. Negative ECG changes after bilateral total adrenalectomy was significantly connected with postoperative hypocorticism.
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