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  • Title: A Polycomb-group gene regulates homeotic gene expression in Arabidopsis.
    Author: Goodrich J, Puangsomlee P, Martin M, Long D, Meyerowitz EM, Coupland G.
    Journal: Nature; 1997 Mar 06; 386(6620):44-51. PubMed ID: 9052779.
    Abstract:
    Cell fate is determined when the commitment of cells to a particular fate is autonomously maintained, irrespective of their environment. In Drosophila, fate determination is maintained through the action of the Polycomb-group and trithorax-group genes, which are required so that states of homeotic gene activity are inherited through cell division. It is shown here that the CURLY LEAF gene of Arabidopsis is necessary for stable repression of a floral homeotic gene and encodes a protein with homology to the product of the Polycomb-group gene Enhancer of zeste. We suggest that Polycomb-group genes have a similar role in fate determination in plants and animals.
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