These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Induction of dual infections in newborn and three-week-old pigs by use of two plaque size variants of porcine reproductive and respiratory syndrome virus.
    Author: Park BK, Joo HS.
    Journal: Am J Vet Res; 1997 Mar; 58(3):257-9. PubMed ID: 9055970.
    Abstract:
    OBJECTIVE: To determine whether pigs can be dually infected with different plaque variants of porcine reproductive and respiratory syndrome virus (PRRSV). ANIMALS: 2 pregnant sows, 20 newborn pigs, and 20 three-week-old pigs. PROCEDURE: The 2 late-term pregnant sows were inoculated with the PRRSV small-plaque variant MN-Hs, and their pigs were challenge exposed at 7 days of age with the PRRSV large-plaque variant MN-HI. In addition, twelve 3-week-old pigs were inoculated with MN-Hs virus. Two groups of the pigs were challenge exposed with MN-HI virus at 14 and 42 days after initial inoculation. Virus was isolated from the pigs at various intervals, plaque sizes were examined, and serologic testing was performed. RESULTS: From the 2 groups of ten 7-day-old pigs, small-plaque PRRSV was isolated form 8 and 10 pigs. After subsequent challenge exposure, dual infections were diagnosed in 3 of 10 inoculated and 4 of 10 contact control pigs. In 3-week-old pigs infected with MN-Hs virus, dual infections were documented in 2 of 6 pigs when challenge exposed 14 days after initial infection. Virus was not isolated from sera of another 6 pigs challenge exposed 42 days after initial infection. Serum neutralization antibody was detected in all 6 pigs at challenge exposure. CONCLUSIONS: Dual infections were documented in viremic newborn pigs and 3-week-old pigs, using 2 plaque variants of PRRSV.
    [Abstract] [Full Text] [Related] [New Search]