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  • Title: Mixed-cryoglobulinemia associated with cutaneous vasculitis and pulmonary symptoms.
    Author: Konishi M, Ohosone Y, Matsumura M, Oyamada Y, Yamaguchi K, Kawahara Y, Mimori T, Ikeda Y.
    Journal: Intern Med; 1997 Jan; 36(1):62-7. PubMed ID: 9058105.
    Abstract:
    A 45-year-old Japanese man with Sjögren's syndrome developed recurrent skin ulcers, palpable purpura, and dyspnea. Serum mixed-type cryoglobulin level was elevated. A biopsy of his skin lesion showed the characteristic leukocytoclastic vasculitis of mixed-type cryoglobulinemia. Dyspnea, skin ulcers, and purpura resolved along with a reduction in the serum cryoglobulin level after prednisolone administration. This patient demonstrated cryoglobulinemia-associated vasculitis, as well as possible cryoglobulinemia-associated pulmonary symptoms.
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