These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: HLA-DRB1*04 high resolution typing.
    Author: Bouwens-Rombouts AG, Verduyn W, Versluis LF, Schreuder GM, Tilanus MG, Giphart M.
    Journal: Exp Clin Immunogenet; 1996; 13(2):84-91. PubMed ID: 9063700.
    Abstract:
    High resolution typing for HLA-DR4 is required to identify the individual subtypes. In this study a panel of DR4-positive samples was typed by both sequencing-based typing (SBT) and oligohybridization (PCR sequence-specific oligonucleotide; PCR-SSO). SBT reveals the highest resolution; moreover, ambiguous DRB1*04 allelic combinations can be resolved by a selective amplification of the individual alleles and subsequent sequencing. An extended DR4-specific PCR-SSO makes high resolution typing possible; however, an additional protocol is required to resolve ambiguities.
    [Abstract] [Full Text] [Related] [New Search]