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  • Title: Synthesis of some new quinazolines and quinoxalines of potential antiinflammatory activity.
    Author: el-Bendary ER, el-Ashmawy MB, Barghash AM, Shehata IA, el-Kerdawy MM.
    Journal: Boll Chim Farm; 1996 Dec; 135(11):617-20. PubMed ID: 9066171.
    Abstract:
    A number of quinazoline derivatives containing basic amine substituents at position 4, as well as new derivatives of triazolo[4,3-alpha]quinoxalines carrying basic amine or carboxylic acid moieties have been synthesized. A tetracyclic imidazotriazoloquinoxaline compound is also reported. Two of the new products (2b and 7b) exhibited good antiinflammatory activity in rats, although inferior to that of indomethacin.
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