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  • Title: Cytoplasmic antineutrophil cytoplasmic antibody-positive vasculitis associated with ulcerative colitis.
    Author: Weir A, Taylor-Robinson SD, Poole S, Pignatelli M, Walters JF, Calam J.
    Journal: Am J Gastroenterol; 1997 Mar; 92(3):506-8. PubMed ID: 9068480.
    Abstract:
    The case of a man with poorly controlled ulcerative colitis, who developed a cytoplasmic antineutrophil cytoplasmic antibody-positive systemic vasculitis, causing small bowel infarction is reported. Antineutrophil cytoplasmic antibodies occur in 50-70% of patients with ulcerative colitis, but are usually of the perinuclear or atypical pattern; the cytoplasmic pattern seen in this case is indicative of systemic vasculitis. A variety of vasculitic diseases have been reported as occurring rarely with ulcerative colitis, but this report is the first description of a cytoplasmic antineutrophil cytoplasmic antibody-positive vasculitis with this association.
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