These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: The role of endogenous nitric oxide synthesis in contractility of term or preterm human myometrium.
    Author: Jones GD, Poston L.
    Journal: Br J Obstet Gynaecol; 1997 Feb; 104(2):241-5. PubMed ID: 9070147.
    Abstract:
    OBJECTIVE: To assess in vitro the role of endogenous myometrial nitric oxide synthesis on human myometrial contraction. DESIGN: Strips of myometrium were mounted in a standard organ bath for assessment of isometric contraction and the response to modulators of nitric oxide synthesis determined. SETTING: A teaching hospital research laboratory. SAMPLE: Women undergoing elective nonlabour caesarean section under regional anaesthesia: 54 at term and seven preterm. RESULTS: Neither addition of L-arginine, the substrate for nitric oxide synthase, nor of an inhibitor of nitric oxide synthase led to any specific change in spontaneous myometrial contraction. CONCLUSION: Endogenous nitric oxide production does not play an important role in the control of human term of preterm nonlabouring uterine smooth muscle contractility.
    [Abstract] [Full Text] [Related] [New Search]