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  • Title: Chromosome analyses in a rhabdoid tumor of the brain.
    Author: Klopfenstein K, Soukup S, Blough R, Mazewski C, Ballard E, Gotwals B, Lampkin B.
    Journal: Cancer Genet Cytogenet; 1997 Feb; 93(2):152-6. PubMed ID: 9078300.
    Abstract:
    A malignant rhabdoid tumor of the brain from a 19-month-old child was studied. Two related clones, 46,XX,-8,+der(8)t(8;22)(p11;q?12)x2,-22,del(22)(q12q?13) and 46,XX-8,+der(8)t(8;22) (p11;q?12) x2,-22,r(22) were found after chromosome analyses of primary and recurrent tumor, and multiple nude mouse passages of the tumor. Breakpoints were studied using FISH.
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