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  • Title: Increases in the effects of albendazole on Echinococcus multilocularis metacestodes by the dipeptide methyl ester (Phe-Phe-OMe).
    Author: Sarciron ME, Walchshofer N, Walbaum S, Arsac C, Descotes J, Petavy AF, Paris J.
    Journal: Am J Trop Med Hyg; 1997 Feb; 56(2):226-30. PubMed ID: 9080884.
    Abstract:
    Three months after infection with Echinococcus multilocularis, Mongolian gerbils were given either the dipeptide methyl ester (Phe-Phe-OMe) or a combination of Phe-Phe-OMe plus albendazole to treat alveolar echinococcosis. Each drug was given orally at the daily dose of 50 mg/kg of body weight following various administration regimens. Histologic and ultrastructural studies of parasites recovered from infected gerbil tissues showed that the dipeptide methyl ester increases the effect of albendazole.
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