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  • Title: Isotretinoin-induced vasculitis imitating polyarteritis nodosa, with perinuclear antineutrophil cytoplasmic antibody in titers correlated with clinical symptoms.
    Author: Chochrad D, Langhendries JP, Stolear JC, Godin J.
    Journal: Rev Rhum Engl Ed; 1997 Feb; 64(2):129-31. PubMed ID: 9085448.
    Abstract:
    The adverse effects of retinoids on bones and joints are being increasingly documented. A case is reported in which isotretinoin was considered responsible for polyarteritis-like vasculitis. Perinuclear antineutrophil cytoplasmic antibodies were present in titers that correlated with clinical and laboratory test abnormalities.
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