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  • Title: Predictive value of obsessive-compulsive personality disorder in antiobsessional pharmacological treatment.
    Author: Cavedini P, Erzegovesi S, Ronchi P, Bellodi L.
    Journal: Eur Neuropsychopharmacol; 1997 Feb; 7(1):45-9. PubMed ID: 9088884.
    Abstract:
    Previous reports have stressed the implication of Personality Disorders as predictors of a poorer treatment outcome in Obsessive-Compulsive Disorder (OCD). The aim of this study was to see whether or not Obsessive-Compulsive Personality Disorder in Obsessive-Compulsive Disorder may be predictive for a poorer outcome to antiobsessive pro-serotonergic pharmacological treatment. For this purpose, 30 OCD patients were divided into two groups according to the presence or absence of Obsessive-Compulsive Personality Disorder. Ten-week standardized treatments with oral SRI drugs were given to look for different outcomes between the two groups in Obsessive-Compulsive symptom severity. At the end of the study we found that the presence of Obsessive-Compulsive Personality Disorder, along with the total number of Personality Disorders, did predict poorer response to pharmacological treatment in OCD.
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