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  • Title: [Cytogenetic research in couples with recurrent spontaneous gestational losses].
    Author: Ceballos-Quintal JM, Pinto-Escalante D, Canto-Herrera J, Castillo-Zapata I.
    Journal: Ginecol Obstet Mex; 1996 Nov; 64():503-7. PubMed ID: 9091427.
    Abstract:
    The most common complication of pregnancy is fetal wastage in any of its manifestations. One of the causes of these reproductive losses is the presence of parental chromosomal aberration. The diagnosis of this cause permits appropriate specific risk for the couple reproduction. In this study, cytogenic analysis were performed to a group of couples with fetal wastage of unknown, to know whether some parental chromosomic aberrations were the etiologic cause of them. Were included 173 couples with two or more reproductive failures. In all couples, metaphase chromosome analysis of peripheral blood was performed, with trypsin-Giemsa banding and C standing. In five women (2.9%) it was found some chromosomal aberration. In all the men and in 168 women the karyotype was normal. In 2.8% of all the subjects it was found some polimorphic chromosome. Routinary chromosomal survey realized to couples with pregnancy looses of unknown cause is important to identify individuals carrying some chromosomal aberration.
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