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  • Title: Diode laser-pumped, frequency-doubled neodymium: YAG laser peripheral iridotomy.
    Author: Abreu MM, Sierra RA, Netland PA.
    Journal: Ophthalmic Surg Lasers; 1997 Apr; 28(4):305-10. PubMed ID: 9101569.
    Abstract:
    BACKGROUND AND OBJECTIVE: The solid-state, continuous-wave, frequency-doubled neodymium: yttrrium-aluminum-garnet (Nd:YAG) laser pumped by a diode laser has several advantages, including air cooling, higher electrical to optical efficiency ratios, portability, and the use of standard 110-V AC electrical service. The authors wanted to evaluate the use of the frequency-doubled Nd:YAG laser for peripheral iridotomy and to compare the tissue interactions of this laser with those of the argon laser. MATERIAL AND METHODS: The authors developed a diode laser-pumped, solid-state, and portable frequency-doubled Nd:YAG laser with a wavelength of 532 nm. The effects of peripheral iridotomy with the frequency-doubled Nd:YAG laser and the argon laser were evaluated in pig eyes in vitro and in rabbit eyes in vivo. Specimens were prepared for light microscopy and scanning electron microscopy. RESULTS: The frequency-doubled Nd:YAG laser successfully created patent iridotomies in all animal eyes treated. The following parameters were used to create penetrating burns: duration of 0.1 second, spot size of 100 microns, and power of 500 mW. In rabbit eyes, the mean number of pulses (P = .16) and the total energy required (P = .21) for iridotomy were not significantly different for the argon laser compared with the frequency-doubled Nd:YAG laser. Gross and histologic evaluation showed similar thermal effects in iris tissues for both the frequency-doubled Nd:YAG laser and the argon laser. The mean zone of thermal damage was 178 +/- 19 microns for the frequency-doubled Nd:YAG laser and 163 +/- 24 microns for the argon laser (P = .14). Scanning electron microscopy showed less disruption of the surface of the lesion for the frequency-doubled Nd:YAG laser compared with the argon laser. CONCLUSIONS: Successful peripheral iridotomy can be performed with the frequency-doubled Nd:YAG laser. Coagulative effects with the frequency-doubled Nd:YAG were similar to those with the argon laser, and the thermal damage zones were comparable in size.
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