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  • Title: [Chemonucleolysis of lumbar disk prolapse. Choice and complications].
    Author: Salvesen R, Hemminghytt S.
    Journal: Tidsskr Nor Laegeforen; 1997 Feb 28; 117(6):807-10. PubMed ID: 9102974.
    Abstract:
    Chemonucleolysis with chymopapain is a well-documented method of treating lumbar disc herniation. In spite of this, only few patients are treated in this way in Norway. We have offered selected patients chemonucleolysis at our hospital since 1985. This article reports the long-term outcomes as regards employment status, back pain and leg pain. We have treated 277 patients. 269 were still alive in October 1995 and were sent a follow-up questionnaire. 257 patients responded, of whom 36 (14%) had undergone surgery later, due to an unsatisfactory outcome of chemonucleolysis. 72% of the patients were fully employed at the time of follow-up. 61% had little or no back pain, while 69% never or only rarely suffered pain in the leg.
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