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  • Title: Incidence of chromosomal abnormalities in 153 pregnancies with ultrasound detected fetal abnormalities.
    Author: Chew S, Anandakumar C, Jayanthi V, Wong YC, Chia D, Arulkumaran S, Ratnam SS.
    Journal: Singapore Med J; 1996 Dec; 37(6):595-7. PubMed ID: 9104057.
    Abstract:
    One hundred and fifty-three patients with fetal abnormalities diagnosed on ultrasound were karyotyped between January 1992 and December 1993. There were 19 (12.4%) fetuses with chromosomal abnormalities. The risk of chromosomal aberrations in the malformed fetuses were increased in the presence of intrauterine growth retardation (15.4%), oligohydramnios (20%) and polyhydramnios (25%). Fetal karyotyping is thus essential in the management of such pregnancies.
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