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  • Title: Characterization of clofazimine metabolites in humans by HPLC-electrospray mass spectrometry.
    Author: Krishna DR, Mamidi RN, Hofmann U, Prabhakar CM.
    Journal: Arzneimittelforschung; 1997 Mar; 47(3):303-6. PubMed ID: 9105550.
    Abstract:
    Clofazimine (CAS 2030-63-9) is an important drug used in the treatment of leprosy. Its important metabolites are investigated by thin layer chromatography (TLC), HPLC (diode array) and HPLC-electrospray mass spectrometry. The resulting analytical data, extraction, isolation and characterization methods are presented. Their applicability is described for human urine analysis.
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