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  • Title: Diffuse tumor microembolism: a rare cause of a high-probability perfusion scan.
    Author: Moores LK, Burrell LM, Morse RW, Belgrave CH, Balingit AG.
    Journal: Chest; 1997 Apr; 111(4):1122-5. PubMed ID: 9106600.
    Abstract:
    Pulmonary tumor embolism is a rare but well-documented cause of respiratory failure in patients with cancer. This entity is probably clinically underrecognized and may represent an important cause of morbidity and mortality. A typical pattern of multiple peripheral subsegmental defects on perfusion lung scanning has been described. We present a case of a unilateral near absence of perfusion in a 53-year-old woman who on autopsy was found to have diffuse tumor microembolism. As new chemotherapeutic agents are developed for the treatment of malignancies, an early diagnosis may become more important. A high-probability perfusion scan should not dissuade the clinician from pursuing further evaluation. Cytologic findings of pulmonary venous blood may be diagnostic.
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