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  • Title: Indirect bright light improves circadian rest-activity rhythm disturbances in demented patients.
    Author: Van Someren EJ, Kessler A, Mirmiran M, Swaab DF.
    Journal: Biol Psychiatry; 1997 May 01; 41(9):955-63. PubMed ID: 9110101.
    Abstract:
    Light is known to be an important modulator of circadian rhythms. We tested the hypothesis than an enduring increase in the daytime environmental illumination level improves rest-activity rhythm disturbances in demented patients. Actigraphy was performed before, during, and after 4 weeks of increased illumination in the living rooms of 22 patients with dementia clinically diagnosed as probable Alzheimer's disease, multi-infarct dementia, dementia associated with alcoholism, or normal pressure hydrocephalus. The results indicated that during increased illumination, the stability of the rest-activity rhythm increased in patients with intact vision, but not in visually impaired patients.
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