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  • Title: Differential expression of bcl-2 and bcl-x during chicken spermatogenesis.
    Author: Vilagrasa X, Mezquita C, Mezquita J.
    Journal: Mol Reprod Dev; 1997 May; 47(1):26-9. PubMed ID: 9110311.
    Abstract:
    We report the isolation and characterization of a chicken testis bcl-XL cDNA coding for a long bcl-x protein with a hydrophobic tail, and the expression of bcl-2 and bcl-x during chicken spermatogenesis. Bcl-2 is highly expressed in embryonic and immature testes enriched in spermatogonia and barely detectable in mature testes, where most of the cells are meiotic and postmeiotic. Bcl-x is expressed in both mature and immature testes, but in a lesser amount in mature testes. Differential expression of bcl-2 and bcl-x during spermatogenesis is consistent with the reported different susceptibility to apoptosis of spermatogonia, and meiotic and postmeiotic cells.
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