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  • Title: [Clinical use of recombinant gonadotropins (FSH, LH, hCG)].
    Author: Antoine JM, Loumaye E, Alvarez S, Merviel P, Cornet D, Mandelbaum J, Salat-Baroux J.
    Journal: Contracept Fertil Sex; 1997 Feb; 25(2):141-6. PubMed ID: 9116774.
    Abstract:
    The production of recombinant gonadotropins is independent of urine collection. They have a high specific activity and a better batch to batch consistency than urinary gonadotropins. In our IVF programme 62 normo-ovulatory patients less than 38 years old, with tubal or idiopathic infertility and normal sperm, were treated by r-FSH and randomized into four groups : with or without LHRH agonist, step-up or step-down stimulation. The overall results were higher in the agonist groups, but did not reveal any significant difference between step-up and step-down stimulation.
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