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  • Title: [Neoton (exogenic phosphocreatinine) in combined therapy of chronic cardiac failure].
    Author: Nedoshivin AO, Perepech NB.
    Journal: Klin Med (Mosk); 1996; 74(9):45-8. PubMed ID: 9121090.
    Abstract:
    To evaluate clinicohemodynamic effect of neoton (exogenic phosphocreatine) given in an intravenous course, the drug was added to standard scheme in 53 patients with chronic cardiac failure (6.0 g/day i.v. drip for 5 days or 3.0 g/day for 10 days). 20 control patients received standard therapy alone. A course neoton produced an increase in the ejection fraction, a reduction in end-diastolic and end-systolic left ventricular volumes. It is recommended to include neoton in the scheme of chronic cardiac failure treatment in the dose 3.0 g/day for 10 days.
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