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  • Title: Meningioma of the foramen magnum: a series of 40 cases.
    Author: George B, Lot G, Boissonnet H.
    Journal: Surg Neurol; 1997 Apr; 47(4):371-9. PubMed ID: 9122842.
    Abstract:
    BACKGROUND: Surgical treatment of foramen magnum meningiomas (FM meningiomas) has been improved by the recently developed posterolateral and anterolateral approaches. The choice of these approaches and the extent of bone resection, however, need to be defined according to the tumor location. METHODS: Over a short period (1980-1993), 40 cases of FM meningiomas were treated either by the posterolateral (N = 31), the anterolateral (N = 5), or the midline posterior approaches (N = 4). The choice of surgical technique (surgical approach, extent of bone drilling, and dural opening) was made according to the tumor location, which is defined by three parameters: the horizontal plane (anterior N = 18, lateral N = 21, and posterior N = 1); the vertebral artery (above N = 4, below N = 20, and on both sides N = 16); the dura mater (intradural N = 24, extradural N = 2, and intraextradural N = 4). RESULTS: Intradural anterior and lateral FM meningiomas were operated by the posterolateral approach. The bone drilling was limited either to the occipital condyle or to the lateral mass of the atlas, depending on whether the tumor location is above or below the vertebral artery, respectively. Intradural posterior meningiomas were treated by the midline posterior approach. FM meningiomas with an extradural component were resected by the anterolateral approach alone or combined with a midline posterior approach. The rate of complete resection was 94% for intradural FM meningiomas and 50% for the extradural ones. FM meningiomas with an extradural component generally have aggressive features invading the adjacent bone and soft tissues; this explains the difficulty of performing a complete resection. The clinical condition improved in 90%, worsened in 7.5%, and did not change in 2.5%. The worsened group consisted of three deaths (one case of air embolism, one case of pulmonary embolism, and one case with preoperative coma and tetraplegia). Similar results were obtained in both anterior and lateral locations. CONCLUSION: FM meningiomas can be completely and safely removed in most cases, using an appropriate surgical technique. The technique must be chosen after precise and correct analysis of the tumor location. The lateral approaches are very effective in the treatment of lateral and anterior FM meningiomas.
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