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  • Title: A pressure system for the microinjection of substances into the brain of awake monkeys.
    Author: Dias EC, Segraves MA.
    Journal: J Neurosci Methods; 1997 Mar; 72(1):43-7. PubMed ID: 9128167.
    Abstract:
    We describe a method for placing pressure microinjections of drugs or anatomical tracers in physiologically defined sites in the brain of awake monkeys. This method provides a means to record neuronal activity from the tip of an injection cannula so that an injection can be made at a physiologically defined location. It uses pressure in a closed system to precisely control the amount of fluid injected and provides a visible means for monitoring injection volume. The injection cannula is easy to make with readily available components and can be used repeatedly for multiple recording sessions and injections.
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