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  • Title: Peroxidation status of erythrocytes and apolipoprotein B containing lipoproteins in hypercholesterolemic subjects.
    Author: Ozdemirler G, Oztezcan S, Toker G, Uysal M.
    Journal: Int J Vitam Nutr Res; 1997; 67(2):130-3. PubMed ID: 9129256.
    Abstract:
    Erythrocyte diene conjugate levels and glutathione peroxidase and superoxide dismutase activities were found unchanged in hypercholesterolemic subjects with plasma cholesterol levels of 240 mg/dl as compared to normocholesterolemics (below 200 mg/dl). However, the susceptibility of VLDL + LDL, apolipoprotein B containing lipoproteins to copper-induced peroxidation and plasma endogenous malondialdehyde levels were increased in hypercholesterolemics. These results indicate that hypercholesterolemia is associated with increased susceptibility of VLDL + LDL to lipid peroxidation.
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