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  • Title: Identification of projections from the central nucleus of the amygdala to the paraventricular nucleus of the hypothalamus which are immunoreactive for corticotrophin-releasing hormone in the rat.
    Author: Marcilhac A, Siaud P.
    Journal: Exp Physiol; 1997 Mar; 82(2):273-81. PubMed ID: 9129941.
    Abstract:
    Corticotrophin-releasing hormone (CRH) immunoreactivity was detected in neurons of the central nucleus of the amygdala that were retrogradely labelled by injection of a fluorescent tracer (True Blue) into the paraventricular nucleus of the hypothalamus (PVN). The double-labelled neurons were located mainly in the medial subdivision of the central nucleus and appeared to comprise less than one-fifth of the descending pathway. These results suggest that CRH may act as a neurotransmitter in the amygdalo-hypothalamic pathway.
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