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  • Title: Sequential arrangement, not transcriptional activity, determines conformational stability of nucleosomes.
    Author: Belikov S, Papatsenko D, Preobrazhenskaya O, Sushkov V, Karpov V.
    Journal: J Biomol Struct Dyn; 1997 Apr; 14(5):651-5. PubMed ID: 9130086.
    Abstract:
    Gel electrophoresis in urea gradient was applied to study the unfolding effect of increasing concentrations of urea on the nucleosome structure. We showed that conformational stability of nucleosomes is determined by nucleotide sequence but not by transcriptional activity of DNA in chromatin.
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