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  • Title: Potent antihepatotoxic activity of dicaffeoyl quinic acids from propolis.
    Author: Basnet P, Matsushige K, Hase K, Kadota S, Namba T.
    Journal: Biol Pharm Bull; 1996 Apr; 19(4):655-7. PubMed ID: 9132180.
    Abstract:
    Hepatoprotective activity guided chemical analyses led to the isolation of two dicaffeoyl quinic acid derivatives, methyl 3,4-di-O-caffeoyl quinate (1) and 3,4-di-O-caffeoyl quinic acid (2) from water extract of propolis, and their structures were determined by the use of 2D NMR. These compounds were stronger antihepatotoxic agents than glycyrrhizin.
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