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  • Title: [Immunoglobulin A levels in the saliva in patients with periodontal disease].
    Author: Bokor M.
    Journal: Med Pregl; 1997; 50(1-2):9-11. PubMed ID: 9132555.
    Abstract:
    The objective of this study was to establish the concentration of immunoglobulin A in saliva and to determine a possible connection between this concentration and the intensity of gingival inflammation. The study comprised 30 healthy persons with a mean age of 37.5 years in whom periodontitis was diagnosed after clinical examination and x-ray analysis. The control group consisted of 30 healthy persons with a mean age of 23.0 years with healthy periodontium. The intensity of clinical gingival inflammation was determined by gingival index after Loben. On the basis of the gingival index values the examinees were divided into three groups. Immunoglobulin A concentration was determined in mixed, nonstimulated saliva by method of nephelometry. Average value of immunoglobulin A in saliva of periodontitis patients was 0.30 g/l and it is significantly lower than in the control group (p < 0.001). It has been established that in persons with increased intensity of gingival inflammation values of immunoglobulin A in the saliva are decreased.
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