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  • Title: beta-Endorphin secretion of arginine vasopressin in vivo.
    Author: Weitzman RE, Fisher DA, Minick S, Ling N, Guillemin R.
    Journal: Endocrinology; 1977 Nov; 101(5):1643-6. PubMed ID: 913330.
    Abstract:
    The effect of beta-endorphin upon plasma arg8-vasopressin release was studied in vivo in rabbits and in vitro in rat neural lobes. Following intravenous administration of 200 mug/kg synthetic beta-endorphin plasma AVP rose significantly by five minutes after injection and remained elevated for twenty-five minutes compared to controls. In contrast beta-endorphin had no significant effect on AVP release from isolated rat neural lobes in vitro. beta-Endorphin stimulates AVP secretion in vivo, but this is not due to a direct action upon the neural lobe.
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