These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: "Fast isoamylases" in the parotid saliva of children with cystic fibrosis and heterozygous carriers.
    Author: Doering KM, Arglebe C, Lubahn H, Chilla R.
    Journal: Eur J Pediatr; 1977 Oct 12; 126(3):185-8. PubMed ID: 913437.
    Abstract:
    On electrophoresis, parotid saliva always exhibits a basic pattern of 6 isoamylases. Additional faster migrating isoamylases occur in varying numbers. These "fast isoamylases" are generated, at least in part, by deamidation. Compared with juvenile and adult controls, a significantly greater number of "fast isoamylases" was found in the parotid saliva of children with cystic fibrosis and their healthy heterozygous parents. A shift in the equilibrium between amidation and deamidation is discussed in terms of its possible connection with the metabolic defect responsible for cystic fibrosis.
    [Abstract] [Full Text] [Related] [New Search]