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  • Title: Unilateral megalencephaly in linear nevus sebaceous syndrome: a neuroradiological case report.
    Author: Wakabayashi C, Maehara T, Shimamura T, Cho N, Iizuka Y, Irimoto M, Niijima S.
    Journal: Radiat Med; 1997; 15(1):65-9. PubMed ID: 9134588.
    Abstract:
    We report a case of linear nevus sebaceous syndrome with seizure, mental retardation, and hemiparesis. Magnetic resonance imaging (MRI) clearly demonstrated associated brain malformations of unilateral megalencephaly with cortical dysplasia and white matter change ipsilateral to the sebaceous nevi of the face and neck. Although magnetic resonance angiography (MRA) demonstrated only distortion of the main cerebral arteries without any occlusive or dysplastic findings, single photon emission computed tomography (SPECT) using [123I]N-Isopropyl-p-iodoamphetamine (IMP) revealed hypoperfusion in the affected cerebral hemisphere.
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