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  • Title: The integration host factor-DNA complex upstream of the early promoter of bacteriophage Mu is functionally symmetric.
    Author: van Ulsen P, Hillebrand M, Zulianello L, van de Putte P, Goosen N.
    Journal: J Bacteriol; 1997 May; 179(9):3073-5. PubMed ID: 9139933.
    Abstract:
    Inversion of the ihf site in the promoter region of the early promoter of bacteriophage Mu did not influence the integration host factor (IHF)-mediated functions. IHF bound to this inverted site could counteract H-NS-mediated repression, directly activate transcription, and support lytic growth of bacteriophage Mu. This implies that the IHF heterodimer and its asymmetrical binding site form a functionally symmetrical complex.
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