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  • Title: [Pathology and clinical aspects of retarded child development. Diagnosis and therapy of defective development].
    Author: Senft HH, Kugener H, Korte W.
    Journal: Fortschr Med; 1977 Oct 20; 95(39):2397-402. PubMed ID: 914199.
    Abstract:
    21 cases of "small for date" pregnancies were analysed. Serial ultrasonic tracings and determinations of total estrogen excretion in the 24-hour-urine and of serum HPL concentration were carried out. The fetal heart rate was measured by cardiotocogram. Retrospectively, the patients were divided into 3 groups according to birth weight. All patients were treated with a combination of Complamin, Calciparin and Partusisten. Fetal growth retardation could not be stopped by this treatment; there was, however, definite fetal weight gain following long term therapy. Results of HPL and total estrogen determinations were inconclusive; in most cases, however, a fall of concentrations was observed. Following long term therapy a rise in concentration up to almost normal values was seen. The positive effect of therapy was best shown by serial cardiotograms.
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