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  • Title: [Possible use of erythrocyte antioxidant enzymes as markers of the course of disease in patients with hemoblastoses].
    Author: Kumerova AO, Petukhov VI, Shkesters AP, Silova AA, Letse AG.
    Journal: Vopr Med Khim; 1996; 42(2):144-7. PubMed ID: 9148601.
    Abstract:
    Blood and erythrocytes of 50 healthy volunteers and 105 patients with different forms of hemoblastoses were investigated. 54 patients had acute phase, 51 patients--remission stage of disease. Essential differences in the activity of antioxidant enzymes (SOD, CAT, GSH-Px) were detected and compared with content of MDA and degree of anaemia. Acute phase had more significantly alteration of antioxidant defence: diverse changes of the activity of SOD and CAT, significantly inhibition of GSH-Px, the high level of MDA and increased degree of anaemia.
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