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  • Title: Crohn's disease and gastrocnemius vasculitis: two new cases.
    Author: Disdier P, Swiader L, Harlé JR, Pellissier JF, Figarella-Branger D, Veit V, Gérolami A, Arlet Ph, Weiller PJ.
    Journal: Am J Gastroenterol; 1997 May; 92(5):880-2. PubMed ID: 9149206.
    Abstract:
    We report two cases of gastrocnemius muscle vasculitis revealing Crohn's disease. Gastrocnemius muscle biopsy evidenced a necrotizing vasculitis resembling panarteritis nodosa in one case; a nonnecrotizing vasculitis was found in the other case. Neither of the patients had systemic vasculitic involvement, and the muscle disease resembled calf muscle-located panarteritis nodosa. Our literature review shows five cases of calf-located myalgia occurring during Crohn's disease characterized by heterogenous histopathological findings including vasculitic and myositic lesions. Thus, faced with calf-located myalgia with vasculitis or myositis, a search for Crohn's disease is probably necessary to determine precisely the frequency and the etiopathogenic mechanisms of this association.
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