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  • Title: A linkage map of the rat genome derived from three F2 crosses.
    Author: Bihoreau MT, Gauguier D, Kato N, Hyne G, Lindpaintner K, Rapp JP, James MR, Lathrop GM.
    Journal: Genome Res; 1997 May; 7(5):434-40. PubMed ID: 9149940.
    Abstract:
    We report the construction of a dense linkage map of the rat genome integrating 767 simple sequence length polymorphism markers, combined over three crosses with high rates of polymorphism. F2 populations from WKY x S (n = 159), BN x S (n = 91), and BN x GK (n = 139) were selected and genotyped for combinations of microsatellite markers. The loci define 21 linkage groups corresponding to the 20 rat autosomal chromosomes and the X chromosome. The map spans a genetic length of 1998 cM. This combined linkage map should facilitate the advancement of genetic studies for a wide variety of rat models characterized for complex phenotypes.
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